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The San Francisco 49ers (-3.5) will be facing off with the Seattle Seahawks (+3.5) to kick off Week 15. The game is in Seattle so the Seahawks will have the 12th man behind them in what feels like a must-win.

San Francisco comes in with seventh-round rookie quarterback Brock Purdy at the helm. He has been impressive since he took over as the starter, but will be on the road for the first time. He will also be without the dynamic Deebo Samuel as...

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